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Hirugen

Catalog No.: A95071
Anticoagulant Protein
Hirugen is a synthetic derivative of hirudin, a natural anticoagulant protein derived from leeches. It functions by specifically inhibiting thrombin, thereby preventing the conversion of fibrinogen to fibrin in the clotting cascade. Hirugen is utilized in various research applications to study blood coagulation mechanisms and the development of anticoagulant therapies. Its potency and specificity make it a valuable tool for investigating thrombotic diseases and potential treatments.
Hirugen 121822-23-9 Anticoagulant Protein
Grouped product items
Size Price Stock Qty
1mg
$80.00
In stock
5mg
$205.00
In stock
10mg
$335.00
In stock
25mg
$1,275.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHirugen is a synthetic derivative of hirudin, a natural anticoagulant protein derived from leeches. It functions by specifically inhibiting thrombin, thereby preventing the conversion of fibrinogen to fibrin in the clotting cascade. Hirugen is utilized in various research applications to study blood coagulation mechanisms and the development of anticoagulant therapies. Its potency and specificity make it a valuable tool for investigating thrombotic diseases and potential treatments.
Product Information
Catalog NumA95071
FormulaC65H91N13O28S
Molecular Weight1534.55
CAS Number121822-23-9
SequenceAsn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-{SO3H-Tyr}-Leu
Sequence shorteningNGDFEEIPEE-{SO3H-Tyr}-L
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(CNC([C@H](CC(N)=O)N)=O)=O)CC(O)=O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)[C@H](CC)C)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(OS(=O)(=O)O)C=C3)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC2
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