Fig. 1 · Structure
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HJ-4
Anti-cancer Agent
HJ-4 is a derivative of Piperine that functions as a potent anti-cancer agent. It effectively inhibits the proliferation of colorectal cancer (CRC) cells by reducing colony formation and DNA synthesis in a dose-dependent manner. Additionally, HJ-4 significantly suppresses adhesion, migration, and invasion of CRC cells while inducing apoptosis. The compound demonstrates notable anti-tumor activity in the chicken embryo chorioallantoic membrane (CAM) model with implanted HCT116/SW480 tumor spheroids, making it a valuable tool for CRC research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1313741-00-2 |
| Applications | Anti-cancer Agent |
| Formula | C23H24N2O4 |
| Molecular Weight | 392.45 |
| SMILES | COC1=CC=CC=C1N2CCN(CC2)C(/C=C/C=C/C3=CC4=C(OCO4)C=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.