Fig. 1 · Structure

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HMGB1-IN-3

HMGB1 Inhibitor

HMGB1-IN-3 is a potent inhibitor of high mobility group protein 1 (HMGB1). This glycyrrhizic acid derivative demonstrates significant biological activity, making it a valuable tool for research into intracerebral hemorrhage and related conditions. Its ability to modulate HMGB1 signaling pathways enables exploration of its role in inflammation and cell death processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 5195-71-1
Applications HMGB1 Inhibitor
Formula C31H46O4
Molecular Weight 482.69
SMILES
C[C@]1(C(OC)=O)CC[C@]([C@@]2([H])C1)(C)CC[C@@](C2=C3)(C)[C@]4(C)CC[C@@]5([H])C(C)(C)C(CC[C@]5(C)[C@@]4([H])C3=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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