Fig. 1 · Structure

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hOAT-IN-1

hOAT Inhibitor

hOAT-IN-1 is a selective inhibitor of human ornithine aminotransferase (hOAT), functioning as a time-dependent mechanical inhibitor. It facilitates the formation of a stable pyridoxal phosphate (PLP) adduct with hOAT, leading to permanent occupation of the enzyme's active site. This compound is valuable for research into the mechanisms of lung cell carcinoma and its potential therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3057092-65-3
Applications hOAT Inhibitor
Formula C7H9F2NO2
Molecular Weight 177.15
SMILES
O=C(C1=C[C@H](N)CC(F)(F)C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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