Fig. 1 · Structure

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Homo-PROTAC pVHL30 degrader 1

pVHL30 degrader

Homo-PROTAC pVHL30 degrader 1 is a potent pVHL30 degrader based on PROTAC.

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Biological Activity

Target & Activity

Target Activity Value
VHL  

Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 2244684-49-7
Applications pVHL30 degrader
Formula C58H82N8O14S2
Molecular Weight 1179.45
SMILES
CC1=C(C2=CC=C(CNC([C@@H]3C[C@@]([H])(O)CN3C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)C[C@@]([H])(O)C4)=O)=O)=O)=O)=O)C=C2)SC=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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