Fig. 1 · Structure

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HP1-IN-2

HP1 Inhibitor

HP1-IN-2 is a small molecule inhibitor targeting the interaction between HP1 and H3K9me3, exhibiting an IC50 of 18.1 μM. This compound is valuable for investigating the biological roles of HP1 in various cancer types characterized by HP1 overexpression. Its application in research can enhance the understanding of cancer mechanisms and potential therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1385556-53-5
Applications HP1 Inhibitor
Formula C19H20N2O4
Molecular Weight 340.37
SMILES
O=[N+]([O-])C1=CC=C(CN2[C@@H](C3=CC(OCCO4)=C4C=C3)CCC2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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