Fig. 1 · Structure
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HPPE
Bach1 Inhibitor
HPPE is an orally active inhibitor of Bach1, a transcription factor within the cap'n'collar (CNC-bZip) family that plays a crucial role in regulating mitochondrial metabolism and glucose utilization. By inhibiting Bach1, HPPE has the potential to influence various biological pathways and may be valuable for research in conditions such as psoriasis, multiple sclerosis, and chronic obstructive pulmonary disease (COPD).
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1325721-55-8 |
| Applications | Bach1 Inhibitor |
| Formula | C21H20F3N5O3S |
| Molecular Weight | 479.48 |
| Synonyms | Bach1-IN-1 |
| SMILES | O=C(C1=CC(N=C(N2C)NC3=NC4=C(S3)C=C(C(F)(F)F)C=C4)=C2C=C1)NCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.