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HPSE1-IN-1

HPSE1 Inhibitor

HPSE1-IN-1 is a selective inhibitor of Heparanase-1 (HPSE1), which plays a crucial role in the degradation of heparan sulfate and extracellular matrix remodeling. This compound exhibits moderate inhibitory activity against exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA). HPSE1-IN-1 is primarily utilized in research applications focusing on cancer progression, inflammation, and tissue remodeling associated with various pathologies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2876926-29-1
Applications	HPSE1 Inhibitor
Formula	C₃₀H₃₀N₂O₆
Molecular Weight	514.57
SMILES	OC([C@H]1N2C([C@@H]([C@H]([C@@H]1OCCC3=CC=CC=C3)O)O)=NC(CCC4=CC(OC5=CC=CC=C5)=CC=C4)=C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.