Fig. 1 · Structure

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HPSE1-IN-2

HPSE1 Inhibitor

HPSE1-IN-2 is a potent inhibitor of Heparanase-1 (HPSE1), a key enzyme involved in the degradation of heparan sulfate. In addition to its primary action, HPSE1-IN-2 also exhibits inhibitory activity against exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA). This compound is useful for studies aimed at understanding the biological role of heparan sulfate in various pathological conditions and for exploring therapeutic strategies targeting HPSE1-related pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2876926-27-9
Applications HPSE1 Inhibitor
Formula C23H24N2O6
Molecular Weight 424.45
SMILES
CO[C@H]1[C@@H]([C@H](C2=NC(CCC3=CC(OC4=CC=CC=C4)=CC=C3)=CN2[C@@H]1C(O)=O)O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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