Fig. 1 · Structure
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HPV18-IN-1
HPV18 Inhibitor
HPV18-IN-1 is a selective inhibitor of Human Papillomavirus type 18 (HPV18) that effectively disrupts the E7-Rb-E2F signaling pathway. This compound demonstrates significant activity in preventing the premature cell cycle progression and aberrant proliferation of cervical cancer cells. HPV18-IN-1 is valuable for research into HPV-related cancers and provides insights into therapeutic strategies against oncogenic pathways linked to HPV18.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 331851-78-6 |
| Applications | HPV18 Inhibitor |
| Formula | C14H10N4OS |
| Molecular Weight | 282.32 |
| SMILES | NC1=CC=C(OC(C2=CC=C3N=C(N)SC3=C2)=N4)C4=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.