Fig. 1 · Structure
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HQ005
CCNK Ddegrader
HQ005 is a potent CCNK degrader, exhibiting a DC50 value of 0.041 µM. This molecular-glue degrader facilitates the interaction between CCNK and components of the ubiquitin-proteasome system, leading to targeted protein degradation. It is primarily utilized in research applications focusing on protein regulation and cellular signaling pathways involving CCNK.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2750644-31-4 |
| Applications | CCNK Ddegrader |
| Formula | C15H15N5O2S2 |
| Molecular Weight | 361.44 |
| SMILES | O=C(CC1=CSC(NC2=CC=CC(CO)=N2)=N1)NC3=NC=C(C)S3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.