Documents & Downloads

HRZ-01-082-5

SALL4/OSR1 Dual Molecular Glue Degrader

HRZ-01-082-5 is a dual-functional molecular glue degrader targeting SALL4 and OSR1, exhibiting a DC50 of 4.8 nM for OSR1. This compound effectively induces the degradation of both SALL4 and OSR1 via the CRBN mechanism. HRZ-01-082-5 is applicable in the study of heart and urogenital development as well as in cancer research, providing valuable insights into these critical biological processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Degrader
CAS Number	3090685-19-8
Applications	SALL4/OSR1 Dual Molecular Glue Degrader
Formula	C₂₇H₂₆N₆O₄S
Molecular Weight	530.60
SMILES	O=C1NC(C(CC1)N2C(C3=CC=C(C4=C(NC56CC7CC(C6)CC(C5)C7)N8N=CSC8=N4)C=C3C2=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.