Fig. 1 · Structure

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HSD17B13 degrader 2

Ligand for Target Protein for PROTAC

HSD17B13 degrader 2 is a PROTAC ligand specifically designed to target the HSD17B13 protein. This compound facilitates the selective degradation of HSD17B13, enabling researchers to study its biological functions and therapeutic potential. It serves as a key tool for the synthesis of additional PROTACs, including HSD17B13 degrader 1, thereby expanding the repertoire of strategies for targeted protein degradation in chemical biology.

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Specifications

Manufacturer Adooq Bioscience
Actions Degrader
CAS Number 3035000-69-9
Applications Ligand for Target Protein for PROTAC
Formula C21H19ClF3N3O2
Molecular Weight 437.84
SMILES
O=C(C1=C(C(F)=C(C(F)=C1)O)F)NC[C@@H](CC2)CC[C@H]2N3C=C4C(C=C(Cl)C=C4)=N3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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