Fig. 1 · Structure

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HSD17B13-IN-102

Cat. No. A69038 CAS 2770246-34-7

HSD17B13 Inhibitor

HSD17B13-IN-102 is a potent inhibitor of the enzyme hydroxysteroid dehydrogenase 17 beta 13 (HSD17B13), demonstrating an IC50 value of less than 0.1 μM with estradiol. This compound is instrumental in research focused on steroid metabolism and associated diseases, particularly in the context of liver function and metabolic disorders. Its selective inhibition provides a valuable tool for investigating the biological roles of HSD17B13 in various physiological and pathological conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2770246-34-7
Applications HSD17B13 Inhibitor
Formula C20H12Cl3F3N2O4S
Molecular Weight 539.74
SMILES
OC1=C(Cl)C=C(C(NC2=C(C(NCC3=CC=CC=C3OC(F)(F)F)=O)SC(Cl)=C2)=O)C=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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