Fig. 1 · Structure

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HSD17B13-IN-104

Cat. No. A69069 CAS 3075100-76-1

HSD17B13 Inhibitor

HSD17B13-IN-104 is a potent and selective inhibitor of HSD17B13, exhibiting an IC50 of 2.5 nM. This compound effectively modulates hepatic lipid metabolism by targeting the SREBP-1c/FAS signaling pathway, thereby reducing hepatic lipid accumulation. HSD17B13-IN-104 holds potential for advancing research on metabolic dysfunction-associated steatohepatitis and related conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3075100-76-1
Applications HSD17B13 Inhibitor
Formula C21H18ClF3N2O2S
Molecular Weight 454.89
SMILES
O=C(C1=C(C)N=C(S1)C2=CC(F)=C(F)C(O)=C2F)N(C(C)C)CC3=CC=C(C=C3)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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