Fig. 1 · Structure

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HSD17B13-IN-105

Cat. No. A69063 CAS 3012624-88-0

17BHSD13 Inhibitor

HSD17B13-IN-105 is a selective inhibitor of 17β-hydroxysteroid dehydrogenase 13 (17BHSD13), exhibiting an IC50 value of 0.036 μM and notable selectivity against 17BHSD4 with an IC50 of 31.5 μM. This compound is valuable for research applications targeting liver diseases, particularly non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Its specificity and potent inhibition profile make it a significant tool for studying the biochemical pathways involved in these conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3012624-88-0
Applications 17BHSD13 Inhibitor
Formula C15H14F3N3O4
Molecular Weight 357.28
SMILES
O=C(N1C[C@@H](C)O[C@@H](C)C1)C2=NOC(C3=CC(F)=C(F)C(O)=C3F)=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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