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HSD17B13-IN-12

Name: HSD17B13-IN-12
Brand: Adooq Bioscience
SKU: A69077
Availability: OutOfStock

Cat. No. A69077 CAS 2758802-04-7

HSD17B13 Inhibitor

HSD17B13-IN-12 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 0.1 μM for both leukotriene B3 and estradiol. This compound is valuable for studying liver diseases, metabolic disorders, and cardiovascular conditions, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its targeted inhibition offers insights into the biochemical pathways associated with these health issues.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2758802-04-7
Applications	HSD17B13 Inhibitor
Formula	C₁₈H₂₁ClN₂O₃S
Molecular Weight	380.89
SMILES	O=C(NCCC(C)(C)C)C1=C(NC(C2=CC(Cl)=C(O)C=C2)=O)C=CS1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.