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HSD17B13-IN-14

Name: HSD17B13-IN-14
Brand: Adooq Bioscience
SKU: A69054
Availability: OutOfStock

Cat. No. A69054 CAS 2758802-05-8

HSD17B13 Inhibitor

HSD17B13-IN-14 is a selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is valuable for research into hepatic conditions, metabolic diseases, and cardiovascular disorders, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its potent inhibition of HSD17B13 makes it an important tool for studying the underlying mechanisms of these diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2758802-05-8
Applications	HSD17B13 Inhibitor
Formula	C₂₁H₁₆ClN₃O₃S
Molecular Weight	425.89
SMILES	O=C(C1=C(NC(C2=CC=C(O)C(Cl)=C2)=O)C=CS1)NCC3=CNC4=C3C=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.