HSD17B13-IN-14 is a selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is valuable for research into hepatic conditions, metabolic diseases, and cardiovascular disorders, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its potent inhibition of HSD17B13 makes it an important tool for studying the underlying mechanisms of these diseases.
HSD17B13-IN-14 is a selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is valuable for research into hepatic conditions, metabolic diseases, and cardiovascular disorders, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its potent inhibition of HSD17B13 makes it an important tool for studying the underlying mechanisms of these diseases.
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