HSD17B13-IN-15 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is of significant interest in the study of various liver diseases, including non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), as well as metabolic and cardiovascular disorders. HSD17B13-IN-15 provides valuable insights for research related to drug-induced liver injury (DILI) and potential therapeutic interventions.
HSD17B13-IN-15 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 1 μM for leukotriene B3 and ≤ 0.1 μM for estradiol. This compound is of significant interest in the study of various liver diseases, including non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), as well as metabolic and cardiovascular disorders. HSD17B13-IN-15 provides valuable insights for research related to drug-induced liver injury (DILI) and potential therapeutic interventions.
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