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HSD17B13-IN-16

Name: HSD17B13-IN-16
Brand: Adooq Bioscience
SKU: A69039
Availability: OutOfStock

Cat. No. A69039 CAS 2758802-09-2

17β-HSD Inhibitor

HSD17B13-IN-16 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 μM for estradiol and less than 1 μM for leukotriene B3. This compound has significant relevance in the study of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH). HSD17B13-IN-16 serves as a valuable tool for researchers investigating metabolic disorders and potential therapeutic interventions in liver diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2758802-09-2
Applications	17β-HSD Inhibitor
Formula	C₂₀H₁₇ClN₂O₄S
Molecular Weight	416.88
SMILES	ClC1=C(O)C=CC(C(NC2=C(C(NCC3=C(OC)C=CC=C3)=O)SC=C2)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.