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HSD17B13-IN-28

Name: HSD17B13-IN-28
Brand: Adooq Bioscience
SKU: A69043
Availability: OutOfStock

Cat. No. A69043 CAS 2770246-42-7

17β-HSD Inhibitor

HSD17B13-IN-28 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 μM for estradiol as substrate. This compound is significant in the study of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH). Its ability to modulate HSD17B13 activity makes it a valuable tool for exploring the metabolic mechanisms underpinning liver disorders and evaluating potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770246-42-7
Applications	17β-HSD Inhibitor
Formula	C₂₃H₁₆Cl₂FN₃O₃
Molecular Weight	472.30
SMILES	O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=C3C(N=CN(C3=O)[C@@H](C4=CC(F)=CC=C4)C)=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.