HSD17B13-IN-29 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 0.1 μM for estradiol. This compound is a valuable tool for research into liver diseases, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI), as well as metabolic and cardiovascular disorders. Its selectivity for HSD17B13 positions it as a significant reagent for investigating therapeutic strategies targeting these conditions.
HSD17B13-IN-29 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 0.1 μM for estradiol. This compound is a valuable tool for research into liver diseases, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI), as well as metabolic and cardiovascular disorders. Its selectivity for HSD17B13 positions it as a significant reagent for investigating therapeutic strategies targeting these conditions.
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