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HSD17B13-IN-30

Name: HSD17B13-IN-30
Brand: Adooq Bioscience
SKU: A69052
Availability: OutOfStock

Cat. No. A69052 CAS 2770246-58-5

17β-HSD Inhibitor

HSD17B13-IN-30 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 of less than 0.1 μM for estradiol substrates. This compound is significant in the study of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH), due to its role in modulating steroid metabolism and fatty liver progression. HSD17B13-IN-30 facilitates research into therapeutic approaches for liver-related metabolic disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770246-58-5
Applications	17β-HSD Inhibitor
Formula	C₂₄H₁₆Cl₂F₃N₃O₄
Molecular Weight	538.30
SMILES	O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=CC(N=C(C)N3CC4=C(OC(F)(F)F)C=CC=C4)=C2C3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.