HSD17B13-IN-31 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 of less than 0.1 μM for estradiol and less than 1 μM for leukotriene B3. This compound is crucial in researching nonalcoholic fatty liver diseases (NAFLDs), particularly nonalcoholic steatohepatitis (NASH), by modulating lipid metabolism and inflammation. HSD17B13-IN-31 serves as a valuable tool for studying the role of HSD17B13 in liver-related disorders and therapeutic interventions.
HSD17B13-IN-31 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 of less than 0.1 μM for estradiol and less than 1 μM for leukotriene B3. This compound is crucial in researching nonalcoholic fatty liver diseases (NAFLDs), particularly nonalcoholic steatohepatitis (NASH), by modulating lipid metabolism and inflammation. HSD17B13-IN-31 serves as a valuable tool for studying the role of HSD17B13 in liver-related disorders and therapeutic interventions.
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