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HSD17B13-IN-40

Name: HSD17B13-IN-40
Brand: Adooq Bioscience
SKU: A69049
Availability: OutOfStock

Cat. No. A69049 CAS 2770246-06-3

17β-HSD Inhibitor

HSD17B13-IN-40 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 of less than 0.1 μM against estradiol substrates. This compound is significant for research related to nonalcoholic fatty liver diseases (NAFLD), particularly nonalcoholic steatohepatitis (NASH), as it may provide insights into the modulation of lipid metabolism and inflammatory pathways. The compound's inhibitory action on HSD17B13 highlights its potential utility in exploring therapeutic strategies for metabolic disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770246-06-3
Applications	17β-HSD Inhibitor
Formula	C₂₃H₁₄Cl₂F₃N₃O₃
Molecular Weight	508.28
SMILES	FC(F)(F)C1=CC=C(CN2C=NC3=CC=CC(NC(C4=CC(Cl)=C(O)C(Cl)=C4)=O)=C3C2=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.