Fig. 1 · Structure

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HSD17B13-IN-45

Cat. No. A69047 CAS 2912452-50-5

HSD17B13 Inhibitor

HSD17B13-IN-45 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 μM for estradiol. This compound is instrumental in exploring pathways associated with liver diseases and metabolic disorders. Researchers can utilize HSD17B13-IN-45 to investigate the role of HSD17B13 in various biological contexts and its potential as a therapeutic target.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2912452-50-5
Applications HSD17B13 Inhibitor
Formula C19H13ClN2O5S2
Molecular Weight 448.90
SMILES
O=C(C1=CC(OC)=C(C=C1)NS(=O)(C2=CSC(C#CC3=CC=CC=C3Cl)=N2)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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