HSD17B13-IN-49 is a selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤ 0.1 μM for estradiol. This compound is valuable for research into various liver-related conditions, including non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), as well as studies on drug-induced liver injury (DILI). Its inhibition of HSD17B13 may provide insights into potential therapeutic strategies for metabolic and cardiovascular disorders linked to liver dysfunction.
HSD17B13-IN-49 is a selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤ 0.1 μM for estradiol. This compound is valuable for research into various liver-related conditions, including non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), as well as studies on drug-induced liver injury (DILI). Its inhibition of HSD17B13 may provide insights into potential therapeutic strategies for metabolic and cardiovascular disorders linked to liver dysfunction.
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