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HSD17B13-IN-54

Name: HSD17B13-IN-54
Brand: Adooq Bioscience
SKU: A69078
Availability: OutOfStock

Cat. No. A69078 CAS 2770247-49-7

HSD17B13 Inhibitor

HSD17B13-IN-54 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. This compound is valuable for investigating the role of HSD17B13 in various pathologies, including liver diseases, metabolic disorders, and cardiovascular conditions such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Additionally, it serves as a useful tool for studying drug-induced liver injury (DILI).

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770247-49-7
Applications	HSD17B13 Inhibitor
Formula	C₂₄H₁₅Cl₂F₄N₃O₃
Molecular Weight	540.29
SMILES	OC1=C(Cl)C=C(C(NC2=CC=C(F)C(N=C(C)N3CC4=CC=CC=C4C(F)(F)F)=C2C3=O)=O)C=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.