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HSD17B13-IN-56-d3

Name: HSD17B13-IN-56-d3
Brand: Adooq Bioscience
SKU: A69101
Availability: OutOfStock

Cat. No. A69101 CAS 2770247-60-2

HSD17B13 Inhibitor

HSD17B13-IN-56-d3 is a selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤ 0.1 μM for estradiol. This compound is valuable for investigating the role of HSD17B13 in liver diseases, metabolic disorders, and cardiovascular conditions, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its inhibitory action makes it a significant tool for exploring therapeutic strategies targeting these conditions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2770247-60-2
Applications	HSD17B13 Inhibitor
Formula	C₂₅H₁₅D₃Cl₂F₃N₃O₄
Molecular Weight	555.35
SMILES	OC1=C(Cl)C=C(C(NC2=CC=C(C)C(N=C(C([2H])([2H])[2H])N3CC4=CC=CC=C4OC(F)(F)F)=C2C3=O)=O)C=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.