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HSD17B13-IN-56

Name: HSD17B13-IN-56
Brand: Adooq Bioscience
SKU: A69061
Availability: OutOfStock

Cat. No. A69061 CAS 2770246-82-5

HSD17B13 Inhibitor

HSD17B13-IN-56 is a selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤ 0.1 μM for estradiol. This compound is crucial for investigating the role of HSD17B13 in various hepatic and metabolic disorders, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its potent inhibition makes it a valuable tool for advancing research in liver pathology and associated cardiovascular conditions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770246-82-5
Applications	HSD17B13 Inhibitor
Formula	C₂₅H₁₈Cl₂F₃N₃O₄
Molecular Weight	552.33
SMILES	O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC(C=CC(C)=C2N=C(C)N3CC4=C(OC(F)(F)F)C=CC=C4)=C2C3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.