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HSD17B13-IN-59

Name: HSD17B13-IN-59
Brand: Adooq Bioscience
SKU: A69107
Availability: OutOfStock

Cat. No. A69107 CAS 2770247-11-3

HSD17B13 Inhibitor

HSD17B13-IN-59 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤ 0.1 μM for estradiol. This compound is valuable for research focused on liver diseases, metabolic disorders, and cardiovascular conditions, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its specific mechanism of action makes it an essential tool in elucidating the role of HSD17B13 in various pathophysiological contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770247-11-3
Applications	HSD17B13 Inhibitor
Formula	C₂₄H₁₇Cl₂N₅O₃
Molecular Weight	494.33
SMILES	O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=CC(N=CN3CC4=NN(C)C5=C4C=CC=C5)=C2C3=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.