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HSD17B13-IN-61

Name: HSD17B13-IN-61
Brand: Adooq Bioscience
SKU: A69074
Availability: OutOfStock

Cat. No. A69074 CAS 2770247-26-0

HSD17B13 Inhibitor

HSD17B13-IN-61 is a specific inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of ≤ 0.1 μM for estradiol. This compound is intended for research into liver-related conditions, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI), as well as various metabolic and cardiovascular diseases. Its high potency makes it a valuable tool for investigating the role of HSD17B13 in these disease contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2770247-26-0
Applications	HSD17B13 Inhibitor
Formula	C₂₃H₁₃Cl₂F₄N₃O₄
Molecular Weight	542.27
SMILES	O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=C(C(N=CN3CC4=C(OC(F)(F)F)C=CC=C4)=C2C3=O)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.