Fig. 1 · Structure

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HSD17B13-IN-68

Cat. No. A69086 CAS 3004660-61-8

HSD17B13 Inhibitor

HSD17B13-IN-68 is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating an IC50 value of less than 0.1 μM for estradiol. This compound is valuable for investigating the role of HSD17B13 in liver diseases and metabolic disorders, providing insights into potential therapeutic targets and mechanisms of action in these conditions. Its potency and specificity make it a useful tool for research in endocrinology and metabolic pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3004660-61-8
Applications HSD17B13 Inhibitor
Formula C23H20N6O3S
Molecular Weight 460.51
SMILES
COC1=CC=C(C(C2CC2)=C1)C3=NC4=C(C5=CC=CC(O)=C5S4)C(N3CC6=NN(N=N6)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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