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HSD17B13-IN-7

HSD17B13 Inhibitor

HSD17B13-IN-7 is a selective inhibitor of HSD17B13, exhibiting IC50 values of 0.18 μM and 0.25 μM for β-estradiol and Leukotriene B4, respectively. Additionally, it acts as a potent antagonist of the NMDA NR2B receptor. This compound shows promise for investigation in non-alcoholic fatty liver disease research, making it a valuable tool for studies exploring metabolic disorders and related therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	863564-16-3
Applications	HSD17B13 Inhibitor
Formula	C₂₁H₂₄FNO₄
Molecular Weight	373.42
SMILES	FC1=C(O)C=CC(C(NC[C@]2(O)CC[C@H](COC3=CC=CC=C3)CC2)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.