Fig. 1 · Structure

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HSD17B13-IN-72

Cat. No. A69071 CAS 3004661-16-6

HSD17B13 Inhibitor

HSD17B13-IN-72 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 μM for estradiol. This compound is valuable for studying the role of HSD17B13 in liver diseases and metabolic disorders, facilitating research into potential therapeutic interventions and mechanisms underlying these conditions. Its high specificity makes it an important tool for elucidating the biological pathways associated with steroid metabolism.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3004661-16-6
Applications HSD17B13 Inhibitor
Formula C25H21N3O3S2
Molecular Weight 475.58
SMILES
COC1=CC(C2CC2)=C(C=C1)C3=NC4=C(C5=CC=CC(O)=C5S4)C(N3CC6=CSC(C)=N6)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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