Fig. 1 · Structure

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HSD17B13-IN-77

Cat. No. A69084 CAS 2912459-67-5

HSD17B13 Inhibitor

HSD17B13-IN-77 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of less than 0.1 μM for estradiol. This compound is valuable for research related to liver diseases and metabolic disorders, providing insight into the role of HSD17B13 in various physiological and pathological processes. Its application may enhance understanding of steroid metabolism and its implications in health and disease.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2912459-67-5
Applications HSD17B13 Inhibitor
Formula C27H30F2N2O5S2
Molecular Weight 564.66
SMILES
FC1=C(C=CC([C@H]2CC[C@@H](CC2)C(C)C)=C1C)C3=NC(S(NC4=C(C=C(C(F)=C4)C(O)=O)OC)(=O)=O)=CS3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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