HSD17B13-IN-85 is a potent inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 μM for estradiol. This compound is primarily employed in the study of nonalcoholic fatty liver disease (NAFLD) and offers significant insights into the role of HSD17B13 in metabolic regulation and liver physiology. Its specific inhibition enhances understanding of the enzyme's contribution to various biological processes and potential therapeutic targets in liver-related disorders.
HSD17B13-IN-85 is a potent inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), exhibiting an IC50 of less than 0.1 μM for estradiol. This compound is primarily employed in the study of nonalcoholic fatty liver disease (NAFLD) and offers significant insights into the role of HSD17B13 in metabolic regulation and liver physiology. Its specific inhibition enhances understanding of the enzyme's contribution to various biological processes and potential therapeutic targets in liver-related disorders.
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