Fig. 1 · Structure

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HSD17B13-IN-88

Cat. No. A69092 CAS 2770247-93-1

HSD17B13 Inhibitor

HSD17B13-IN-88 is a potent inhibitor of 17β-Hydroxysteroid dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of ≤0.1 μM for estradiol. This compound selectively modulates steroid hormone metabolism and has significant implications for research in metabolic disorders and liver diseases. Its ability to influence estradiol levels makes it a valuable tool for studying hormone-related pathways and therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2770247-93-1
Applications HSD17B13 Inhibitor
Formula C27H23Cl2N3O3
Molecular Weight 508.40
SMILES
OC1=C(Cl)C=C(C(NC2=C3C(N=C(C)N([C@H]4[C@H](C5=CC=CC=C5)CC4)C3=O)=C(C)C=C2)=O)C=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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