Fig. 1 · Structure
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HSD17B13-IN-89
Cat. No.
A69065
CAS
2770247-94-2
HSD17B13 Inhbitor
HSD17B13-IN-89 is a potent inhibitor of 17β-Hydroxysteroid dehydrogenases (HSD17B13), exhibiting an IC50 of less than 0.1 μM for estradiol. This reagent is primarily utilized in research related to nonalcoholic fatty liver disease (NAFLD), offering valuable insights into the role of HSD17B13 in hepatic metabolism and disease progression. Its specificity and efficacy make it a critical tool for studying the pathophysiology of metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2770247-94-2 |
| Applications | HSD17B13 Inhbitor |
| Formula | C23H13Cl2F4N3O3 |
| Molecular Weight | 526.27 |
| SMILES | OC1=C(Cl)C=C(C(NC2=C3C(N=CN(CC4=C(C(F)(F)F)C=CC=C4)C3=O)=C(F)C=C2)=O)C=C1Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.