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HSD17B13-IN-9

Catalog No.: A68993
HSD17B13 Inhbitor
HSD17B13-IN-9 is a selective inhibitor of 17β-Hydroxysteroid dehydrogenases 13 (HSD17B13), exhibiting an IC50 of 0.01 μM against 50 nM HSD17B13. This compound plays a significant role in the investigation of nonalcoholic fatty liver diseases (NAFLD) by modulating steroid metabolism and related pathways. Its potent inhibitory effects make it a valuable tool for research into hepatic lipid metabolism and associated disorders.
HSD17B13-IN-9 2576690-78-1 HSD17B13 Inhbitor
Grouped product items
Size Price Stock Qty
5mg
$435.00
In stock
10mg
$715.00
In stock
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHSD17B13-IN-9 is a selective inhibitor of 17β-Hydroxysteroid dehydrogenases 13 (HSD17B13), exhibiting an IC50 of 0.01 μM against 50 nM HSD17B13. This compound plays a significant role in the investigation of nonalcoholic fatty liver diseases (NAFLD) by modulating steroid metabolism and related pathways. Its potent inhibitory effects make it a valuable tool for research into hepatic lipid metabolism and associated disorders.
Product Information
Catalog NumA68993
FormulaC22H17F3N2O2S
Molecular Weight430.44
CAS Number2576690-78-1
SMILESCC1=CC=C2C(SC3=C(C2NC(C4=CC=C(NC4=O)C(F)(F)F)=O)C=CC(C)=C3)=C1
Useful Calculator

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Metabolism > 17β-HSD