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HSD17B13-IN-94

Name: HSD17B13-IN-94
Brand: Adooq Bioscience
SKU: A69098
Availability: OutOfStock

Cat. No. A69098 CAS 2848620-90-4

HSD17B13 Inhibitor

HSD17B13-IN-94 is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. This compound is instrumental in the investigation of liver diseases, metabolic disorders, and cardiovascular conditions, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and drug-induced liver injury (DILI). Its selective inhibition of HSD17B13 provides valuable insights into the underlying mechanisms of these diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2848620-90-4
Applications	HSD17B13 Inhibitor
Formula	C₂₁H₂₀ClN₃O₄S
Molecular Weight	445.92
SMILES	OC1=CC=C(C(NC2=C(C(NCCC3=C(OC)C=CC=C3)=O)N=C(C)S2)=O)C=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.