Fig. 1 · Structure

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HSD17B13-IN-95

Cat. No. A69070 CAS 2849338-41-4

HSD17B13 Inhibitor

HSD17B13-IN-95 is a potent inhibitor of 17 β-hydroxysteroid dehydrogenase (HSD17B13), with an IC50 value for estradiol of less than 0.1 μM. This compound is useful in the investigation of nonalcoholic fatty liver disease and other metabolic disorders associated with altered steroid hormone metabolism. Its ability to effectively modulate HSD17B13 activity makes it a valuable tool for research into the biological mechanisms underlying liver function and related pathologies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2849338-41-4
Applications HSD17B13 Inhibitor
Formula C24H16F6N4O4
Molecular Weight 538.40
SMILES
OC1=CC=C(C(NC2=C3C(N=CN(CCC4=CC=CC=C4OC(F)(F)F)C3=O)=CC=C2)=O)N=C1C(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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