Fig. 1 · Structure

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HSD17B13-IN-98

Cat. No. A69106 CAS 2849338-45-8

HSD17B13 Inhibitor

HSD17B13-IN-98 is a potent inhibitor of 17 β-hydroxysteroid dehydrogenase (HSD17B13), demonstrating an IC50 value for estradiol of less than 0.1 μM. This compound is particularly relevant in the investigation of nonalcoholic fatty liver disease, providing valuable insights into the biochemical pathways involved in lipid metabolism and liver function. Its specificity and efficacy make it an essential tool for research focused on metabolic disorders and related therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2849338-45-8
Applications HSD17B13 Inhibitor
Formula C18H20F3N3O3S
Molecular Weight 415.43
SMILES
OC1=C(C(F)(F)F)N=C(C(NC2=C(C(NCCC(C)(C)C)=O)SC=C2)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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