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HSN748

Multikinase Inhibitor

HSN748 is a multikinase inhibitor that effectively targets FLT3, ABL1, RET, PDGFRα/β, MNK1, MNK2, and additional kinases. It demonstrates significant inhibitory effects on the growth of chronic myeloid leukemia and acute myeloid leukemia cell lines. HSN748 serves as a valuable tool for researchers investigating the molecular mechanisms of leukemia and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2409925-53-5
Applications	Multikinase Inhibitor
Formula	C₂₇H₂₄F₃N₇O
Molecular Weight	519.52
SMILES	O=C(C1=CC(C#CC2=CN=C3C=CC=NN23)=CN=C1)NC4=CC=C(CN5CCN(CC5)C)C(C(F)(F)F)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.