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- Haruka Wakasa, .et al. Adverse Effects of High Temperature On Mammary Alveolar Development In Vitro, J Mammary Gland Biol Neoplasia, 2022, Jun;27(2):155-170 PMID: 35581442
Biological Activity
HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.84 mL | 189.18 mL | 378.36 mL |
| 0.5 mM | 7.57 mL | 37.84 mL | 75.67 mL |
| 1 mM | 3.78 mL | 18.92 mL | 37.84 mL |
| 5 mM | 0.76 mL | 3.78 mL | 7.57 mL |
*The above data is based on the productmolecular weight 264.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18874 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 2133499-85-9 |
| Formula | C13H12O4S |
| M. Wt | 264.3 |
| Purity | >98% |
| Synonyms | 0 |
| SMILES | O=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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