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HSP27 inhibitor J2

Catalog No.: A18874

HSP27 inhibitor

HSP27 inhibitor J2

HSP27 inhibitor J2 Chemical Structure

CAS NO. 2133499-85-9

HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof.

Availability: In stock

Package Price Qty
1 mg
$126.00
5 mg
$378.00
10 mg
$644.00
50 mg
$1,932.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Haruka Wakasa, .et al. Adverse Effects of High Temperature On Mammary Alveolar Development In Vitro, J Mammary Gland Biol Neoplasia, 2022, Jun;27(2):155-170 PMID: 35581442

Biological Activity

HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.84 mL 189.18 mL 378.36 mL
0.5 mM 7.57 mL 37.84 mL 75.67 mL
1 mM 3.78 mL 18.92 mL 37.84 mL
5 mM 0.76 mL 3.78 mL 7.57 mL

*The above data is based on the productmolecular weight 264.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18874
Actions Inhibitor
CAS No. 2133499-85-9
Formula C13H12O4S
M. Wt 264.3
Purity >98%
Synonyms 0
SMILES O=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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