Hsp90β decapeptide

Catalog No.: A37589
Tah1 Binding Peptide
Hsp90β decapeptide is derived from the C-terminal region of Hsp90β and features the conserved TPR-domain sequence MEEVD. This peptide effectively binds to the Tah1 protein, exhibiting a binding affinity with a dissociation constant (Kd) of 1.0 μM. Its ability to modulate Hsp90-Tah1 interactions makes Hsp90β decapeptide a valuable tool for researching protein chaperone activity and cellular stress responses.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHsp90β decapeptide is derived from the C-terminal region of Hsp90β and features the conserved TPR-domain sequence MEEVD. This peptide effectively binds to the Tah1 protein, exhibiting a binding affinity with a dissociation constant (Kd) of 1.0 μM. Its ability to modulate Hsp90-Tah1 interactions makes Hsp90β decapeptide a valuable tool for researching protein chaperone activity and cellular stress responses.
Product Information
Catalog NumA37589
FormulaC45H73N13O22S
Molecular Weight1180.20
CAS Number1141872-74-3
SequenceGlu-Asp-Ala-Ser-Arg-Met-Glu-Glu-Val-Asp
Sequence shorteningEDASRMEEVD
SMILES[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C(O)=O)=O)C(C)C)=O)CCC(O)=O)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)N)=O)CC(O)=O)=O)C)=O)CO)=O)CCCNC(=N)N)=O)CCSC)=O)CCC(O)=O
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