Fig. 1 · Structure

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HTL22562

CGRP Receptor Antagonist

HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist that plays a significant role in the study of migraine pathology. It effectively inhibits CGRP receptor activity, which is critical for understanding migraine mechanisms and developing therapeutic strategies. HTL22562 is primarily used in acute research settings to explore the implications of CGRP signaling in headache disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2097085-63-5
Applications CGRP Receptor Antagonist
Formula C40H49N11O5
Molecular Weight 763.89
SMILES
O=C(N1CCC2(OC(NC3=NC=CC=C32)=O)CC1)N[C@H](CC4=CC5=C(NN=C5)C(C)=C4)C(N[C@@H](CC6CCNCC6)C(N7CCN(C8=CC=NC=C8)CC7)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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