Fig. 1 · Structure
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HTS07545
SQOR Inhibitor
HTS07545 is a potent inhibitor of sulfide:quinone oxidoreductase (SQOR), exhibiting an IC50 of 30 nM. This compound effectively reduces the decomposition rate of hydrogen sulfide (H2S), making it a valuable tool in studies of metabolic pathways involving H2S. HTS07545 is particularly relevant for research applications focused on heart failure and pancreatic ductal adenocarcinoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 118666-03-8 |
| Applications | SQOR Inhibitor |
| Formula | C22H18N2O3 |
| Molecular Weight | 358.39 |
| SMILES | N#CC1=C(C2=CC=CC=C2)C=C(C3=CC=CC=C3)N=C1OCC(OCC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.