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HTS10307

ΔFOSB Inhibitor

HTS10307 is a small molecule inhibitor targeting the ΔFOSB transcription factor. It effectively inhibits the binding of ΔFOSB to DNA, showing IC50 values of approximately 3 μM for ΔFOSB/JUND and around 7 μM for ΔFOSB alone. This compound serves as a valuable chemical probe for exploring the involvement of ΔFOSB in various pathological conditions, including drug addiction, Alzheimer’s disease, and Parkinson’s disease.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	81682-91-9
Applications	ΔFOSB Inhibitor
Formula	C₁₄H₈N₂O₂S
Molecular Weight	268.29
SMILES	O=C(N1)C(C#N)=C(C2=CC=CO2)C=C1C3=CC=CS3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.