HTS13286 is a selective inhibitor of aquaporin 9 (AQP9), targeting water and glycerol transport in cells. This compound effectively attenuates lipopolysaccharide (LPS)-induced nitric oxide (NO) production and reduces glucose output in response to inflammatory stimuli. HTS13286 is valuable for research applications related to endotoxin shock and the study of metabolic dysregulation in inflammatory conditions.
HTS13286 is a selective inhibitor of aquaporin 9 (AQP9), targeting water and glycerol transport in cells. This compound effectively attenuates lipopolysaccharide (LPS)-induced nitric oxide (NO) production and reduces glucose output in response to inflammatory stimuli. HTS13286 is valuable for research applications related to endotoxin shock and the study of metabolic dysregulation in inflammatory conditions.
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